Equipment for animal physiology research
Moscow, Zelenograd

Systole: noninvasive blood pressure measurement for rodents

Systola - System of noninvasive measurement of blood pressure (NIBP non-invasive blood pressure) of rats and mice

"Systole" is intended for non-invasive measurement of systolic and diastolic pressure from the tail of rodents of small and medium sizes: rats and mice.

The built-in pomp automatically forces pressure in a tail-cuff until the termination of pulsations of a bloodstream, then, slowly reducing pressure, measures systolic and diastolic pressure on a basis of indications of the infrared sensor of the pulse which is put on a tail of an animal after a cuff.

ATTENTION! It is obligatory to heat the animal for noninvasive measurement of blood pressure in rats and mice. It allows to provide blood circulation in the tail in the necessary volume and to stabilize a bloodstream. It is obligatory to preheat the animal to a temperature of 28-32 C° for 10-15 minutes. Such mode of heating has to be supported during all procedure of measurement of pressure. For heating it is offered to use the heating platform Phlogiston or other suitable system of heating of small animals.


The maximum pressure in the cuff 100 - 300 mmHg. (is specified through the program)
Pressure measurement accuracy 1% (3 mmHg)
Cuffs For rats with a diameter of tail 5-10 mm
For mice with a tail diameter 3-6 mm
Pulse Sensor Infrared
Heart Rate 40-600 beats per minute
Measuring cycle time 30-90 seconds (depends on the pulse rate)
Start-up and emergency termination From the software
Data recording frequency 1000 Hz
Connection interface to PC USB 2.0
Power supply via USB (5V, 400 mA)
Dimensions of control module 190х100х40 mm
Weight 350 g
Computer requirements Microsoft Windows 7 SP1, Windows 10
Warranty 1 year
Production Russia, LLC «Neurobotics»

Specifications and prices

Standard equipment
  • 1-channel non-invasive pressure measurement system,
  • cuff (optional for rats or for mice),
  • infrared pulse sensor,
  • rodent holding device Teremoque (size by choice),
  • spare membranes for cuff (4 pieces)
On request
Heating platform Phlogiston On request
Cuff 5-10 mm (for rats) with a photosensor On request
Cuff 3-6 mm (for mice) with a photosensor On request

Resources and Downloads

Systole software (Version 3.1.2)

Document that the Systole isn't brought in the Federal Registration Service of measuring instruments

Drivers for Windows 7-10

General questions

How long does it take to warm up a rat?
How do you know if a rat is warm enough to take a measurement?
We got a strange result when measuring. With what it can be connected?
How often does Systole device need to be verified?

Systola is not in the list of measuring means (according to the Russian Gosreestr) and doesn't need to verified.

The calibration procedure can be found in the manual.